Meanwhile, hospital sources confirmed that 19 people were killed in the incident.
Witnesses also said there were several casualties. The injured were being shifted to the Jinnah and Civil hospitals.
Television pictures showed a big cloud of smoke over the scene and television reporters said angry worshippers attacked a media vehicle.
The police was urging civilians to move away from the site of the blast.
The procession continued to move forward despite the explosion.
This was the third such incident in the city in the last 48 hours that left several people injured.
Earlier, on Sunday, 30 people including three policemen were injured when a low-intensity bomb exploded during a Muharram procession near Qasba Mor in Orangi town.
Similarly, a procession in Paposhnagar was targeted on Saturday when a Muharram procession was passing through. The incident left 13 people injured, mostly women and children.
Earlier, on Sunday, 30 people including three policemen were injured when a low-intensity bomb exploded during a Muharram procession near Qasba Mor in Orangi town.
Similarly, a procession in Paposhnagar was targeted on Saturday when a Muharram procession was passing through. The incident left 13 people injured, mostly women and children.

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